Metabolism and side effects of ribavirin

3 year ago

67 0

Xi'an Henrikang Biotech Co.,Ltd

 1 min year

Video details

Ribavirin can inhibit the growth of respiratory syncytial virus, influenza virus, hepatitis A virus, adenovirus and other viruses in vitro, but its mechanism is not fully understood. Ribavirin did not alter viral adsorption, invasion, or molting, nor did it induce interferon production. Ribavirin enter the cells infected by the virus rapidly phosphorylation and its product as competitive inhibitors of virus synthetase, inhibition of inosine monosodium phosphate dehydrogenase, influenza virus RNA polymerase and mRNA guanosine transferase, causing cell guanosine triphosphate, damage the virus RNA and protein synthesis, inhibition of viral replication and spread. It may also have immune and neutralizing antibody effects on respiratory syncytial virus. Drug metabolism: The concentration of ribavirin in respiratory secretions was mostly higher than that in blood. This product can enter the red blood cell, and the accumulation of large. The concentration of drugs in cerebrospinal fluid can reach 67% of the blood concentration in the same period after long-term medication. This product can cross the placenta, can also enter the milk. It's metabolized in the liver. Intravenous administration eliminated tl/2 in about 0.5-2 hours. It is mainly excreted through the kidney. The urine excretion rate is 30%-55% at 72-80 hours. The fecal excretion rate in 72 hours is about 15%. The drug can accumulate in red blood cells for weeks.

You May Also Like

Contact Now

If you are interested in the product, contact 2bvideo.com for more information for more information

To:: Xi'an Henrikang Biotech Co.,Ltd

Message:

Submit

Disclaimer：

The information of 2bvideo.com limited shown above is provided by the user or collected on the network. Video 2B does not guarantee the authenticity,accuracy and legitimacy of 2bvideo.com limited information. Video 2B does not involve legal relationships and disputes between users arising from transactions other than secured transactions on this website. Disputes shall be settled by you through negotiation. If you are the person in charge or relevant employee of this enterprise, if you find that the enterprise information is incorrect or want to manage thiscompany, please contact us jacklee1558@gmail.com, after you claim the enterprise, you can obtain management permission, publish supplyand demand information, bring consulting orders, and remove page advertisements.

Xi'an Henrikang Biotech Co.,Ltd

 Audited supplier

1 min

Address: Xian, China

Main Product: Bodybuilding Product, Cosmetic Raw, Veterinary Products, Loss weight Products, Healthcare Products, Vitamins & Enzyme

 Contact now