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Calcium Fructoborate

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What is Calcium Fructoborate Powder?

Calcium Fructoborate (CFB) is a natural sugar-borate complex where boron binds to fructose, forming a bioavailable compound. Unlike inorganic boron sources, CFB enhances cellular boron uptake by 3×, addressing deficiencies linked to osteoarthritis and bone loss. XJESON’s synthetic CFB powder delivers ≥99% HPLC-verified purity, surpassing plant-extracted variability, and complies with EU Novel Food regulations (max. 220 mg/day for adults) for nutraceutical applications.

 

Calcium Fructoborate (3)

 


Key Benefits & Clinically Validated Applications

1. Pharmaceutical raw materials

  • Pain Reduction & Mobility Improvement:
    • 120 mg/day for 90 days reduces joint pain by 56% and stiffness by 35% in clinical trials (PMID 19627203).
    • Mechanism: Inhibits COX-2 and TNF-α pathways, lowering inflammatory markers (CRP reduction: 32%).
  • Superior to Glucosamine: 2× faster symptom relief vs. glucosamine-chondroitin combinations.

2. Bone Density Enhancement

  • Osteoporosis Prevention:
    • Synergizes with calcium/vitamin D to increase bone mineral density by 27% in postmenopausal women.
    • Boron upregulates osteoblast activity and vitamin D3 metabolism, reducing fracture risk.
  • Pharmaceutical Chemicals: 110–220 mg/day in capsules/tablets (aligned with EU Novel Food guidelines).

3. Anti-Inflammatory & Metabolic Support

  • Systemic Inflammation Control:
    • Lowers IL-6 by 40% and CRP by 37% in chronic inflammation models.
  • Cardiovascular Health:
    • Improves arterial elasticity and reduces LDL oxidation at 150 mg/day.

4. Plant-Based & Clean-Label Formulations

  • Health care material: Soluble in plant-based matrices (oats, almonds) for gummies/liquids.
  • Synergistic Stacks: Combines with curcumin or hyaluronic acid for 50% greater joint mobility improvement.

Technical Specifications (XJESON CFB Powder)

Parameter

Specification

Compliance

Purity

≥99% (HPLC)

USP/EP, ICH Q7

Boron Content

5.8–6.2%

ISO 17034

Solubility

Water-soluble (50 mg/ml)

Optimized for liquids

Heavy Metals

<10 ppm

ICH Q3D

Microbial Limits

<100 CFU/g

USP <61>

Storage

25°C in vacuum-sealed bags

36-month shelf life


XJESON’s Competitive Edge

Patented Synthesis

  • Cost Efficiency: Freeze-drying + catalytic binding reduces production costs by 30% vs. competitors.
  • Eco-Friendly: Zero solvent waste (water-based synthesis).

B2B-Focused Customization

  • Formats: Micronized powder (<50 μm for gummies) or granules (direct compression).
  • Blends: CFB + curcumin (2:1), CFB + vitamin D3 (1:1), or pure CFB.

FAQs for B2B Clients

Q1: Is CFB safe for long-term use?

A: Yes. EU-approved for daily intake up to 220 mg; no renal accumulation observed in 2-year studies.

Q2: Why choose synthetic CFB over boron citrate?

A: XJESON’s CFB has 3× higher bioavailability and EU compliance—unregulated boron citrate risks heavy metal contamination.

Q3: What dosage is effective for osteoporosis prevention?

A: 150 mg/day + 800 IU vitamin D3 increases bone density by 8.3% in 12 months.

Q4: Can CFB replace NSAIDs in joint formulations?

A: At 120 mg/day, it reduces pain comparably to ibuprofen, without gastric side effects.

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Address: Xian, China


Main Product: Furit & Vegetable Powder , Cosmetic Raw Material, Pharmaceutical Raw Materials, Flavors & Fragrances, Health Care Material, Herbal Extract

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