Professional supplier of Calcium L-5-Methyltetrahydrofolate (L-5-MTHF-Ca), active folate ingredient for prenatal, multivitamin and nutraceutical formulations. COA, GMP and export support available.
Active Folate Ingredient for Nutraceutical & Supplement Formulations
We support global nutraceutical brands with reliable sourcing, quality documentation and export coordination for active folate ingredients.

Calcium L-5-Methyltetrahydrofolate, also known as L-5-MTHF Calcium, is the biologically active form of folate used in dietary supplements and functional nutrition products.
It is widely applied in:
Compared with conventional folic acid, L-5-MTHF is considered a premium folate ingredient for advanced nutraceutical formulations.

Used in pregnancy and maternal nutrition formulations.
Suitable for premium vitamin blends and daily wellness products.
Commonly used in active folate and methylation support formulas.
Compatible with multiple supplement delivery systems.

| Item | Specification |
|---|---|
| Product Name | Calcium L-5-Methyltetrahydrofolate |
| Synonym | L-5-MTHF Calcium |
| Appearance | Light Yellow Powder |
| Assay | 95%+ |
| CAS No. | 151533-22-1 |
| Grade | Food Grade |
| Test Methods | HPLC |
| Packaging | 1kg / 5kg / 25kg Drum |
|
Test Item |
Specification |
Test Result |
Method |
|
Physical Properties |
— |
— |
— |
|
Appearance |
White to pale yellow crystalline powder |
Complies |
Visual |
|
Identification (HPLC/IR) |
Consistent with reference standard |
Complies |
HPLC/IR |
|
Chemical Assay |
— |
— |
— |
|
Assay (L-5-MTHF-Ca, anhydrous) |
95.0% ~ 102.0% |
99.20% |
HPLC |
|
D-Isomer |
≤ 1.0% |
0.35% |
HPLC |
|
Calcium Content |
7.0% ~ 8.5% |
7.80% |
Titration |
|
Water Content |
≤ 17.0% |
8.50% |
Karl Fischer |
|
Related Substances |
≤ 2.5% |
0.80% |
HPLC |
|
Heavy Metals & Impurity |
— |
— |
— |
|
Lead (Pb) |
≤ 2.0 mg/kg |
< 1.0 mg/kg |
ICP-MS |
|
Arsenic (As) |
≤ 1.0 mg/kg |
< 0.5 mg/kg |
ICP-MS |
|
Residual Solvents |
Complies with USP <467> |
Complies |
GC |
|
Microbiology |
— |
— |
— |
|
Total Aerobic Bacteria |
≤ 1000 CFU/g |
< 100 CFU/g |
Microbial Culture |
|
Yeast & Mold |
≤ 100 CFU/g |
< 10 CFU/g |
Microbial Culture |
|
E. coli |
Negative |
Negative |
Microbial Test |
|
Salmonella |
Negative |
Negative |
Microbial Test |
We connect global supplement brands with reliable Chinese ingredient manufacturing resources.
Our support includes:
No. L-5-MTHF is the active form of folate commonly used in premium nutraceutical products.
We can support:
Standard export packaging includes 1kg foil bags and 25kg drums.
Yes. We support raw material supply as well as customized supplement manufacturing solutions.
Contact us for:

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