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White crystalline powder, freely water-soluble, ≥98% HPLC, single impurity ≤0.5%.
HERSONCARE Tranexamic Acid 98% (INCI: Tranexamic Acid, CAS 1197-18-8) is a cosmetic-grade active supplied as a white crystalline powder, freely soluble in water and practically insoluble in ethanol. It is used in brightening serums, essences, creams and post-procedure care targeting melasma and post-inflammatory hyperpigmentation (PIH).
Two technical points separate this grade from a generic listing. First, the specification is ≥98.0% HPLC with single impurity ≤0.5% — the correct standard for topical cosmetic use. Pharmaceutical grade at ≥99.0% and single impurity ≤0.1% adds drug GMP documentation and cost without a formulation benefit, because TXA acts as a surface-active agent in the epidermis. Second, the mechanism is often mislabelled: TXA is a plasmin inhibitor, not a tyrosinase inhibitor. It blocks plasminogen-to-plasmin conversion in keratinocytes, reducing arachidonic acid and PGE2 release, intercepting the melanogenesis signal before tyrosinase upregulation. This upstream position is why it complements rather than duplicates alpha-arbutin or kojic acid.
Supplied in 25 kg drums with moisture-proof lining, 1 kg to 25 kg custom packaging, MOQ 25 kg. Pairs with Natural Antioxidants and Sodium Hyaluronate for brightening-plus-hydration systems.
Appearance: white crystalline powder, almost tasteless. Solubility: freely soluble in water; practically insoluble in ethanol, acetone and chloroform. Assay: 98.0–101.0% (HPLC, C18 column, 220 nm). Cosmetic grade purity: ≥98.0% HPLC, single impurity ≤0.5%. pH (5% solution): 6.0–8.0. Loss on drying: ≤0.5%. Sulphated ash: ≤0.1%.
Related substances: RRT 1.5 ≤0.2%, RRT 2.1 ≤0.1%, any other individual ≤0.1%, total ≤0.5%. Chlorides: ≤140 ppm. Heavy metals: ≤10 ppm; arsenic ≤2 ppm. Each batch ships with a full HPLC chromatogram, impurity profile and microbiological results on the COA.
pH stability: stable across pH 3.0–8.0; optimal formulation window pH 5.0–7.0. Thermal/storage: 3 years from manufacture in sealed packaging at 15–25°C, protected from moisture and light. Aqueous formulations are prone to time-dependent discolouration; pH control and light-protective packaging are the primary mitigations.
High-purity crystalline powder, suitable for serums and essences.
TXA works at Stage 1 of the melanin cascade: it competitively blocks lysine-binding sites on plasminogen, preventing plasmin-driven arachidonic acid and PGE2 release that would otherwise upregulate tyrosinase. This addresses the inflammatory trigger behind PIH and melasma before pigment production begins — a mechanism no tyrosinase inhibitor replicates. It is a rational partner for alpha-arbutin or niacinamide, not a substitute.
A split-face RCT comparing 3% TXA cream with 4% hydroquinone over 8 weeks found no statistically significant difference in mMASI improvement. Hydroquinone carries risks of paradoxical hyperpigmentation and exogenous ochronosis with prolonged use, and comparative data show higher erythema and irritation rates with HQ, with patient satisfaction favouring TXA. For brands formulating away from hydroquinone, this is a defensible clinical basis.
Cosmetic grade at ≥98% HPLC with single impurity ≤0.5% is the appropriate specification. Pharmaceutical grade at ≥99% adds drug GMP overhead without changing surface plasmin inhibition in the epidermis. The cost difference is real; the formulation benefit is not, unless the target market mandates pharma-grade documentation.
Freely water-soluble, added directly to the water phase. Stable across pH 3.0–8.0, working recommendation pH 5.0–7.0. Compatible with niacinamide, vitamin C derivatives and alpha-arbutin, subject to pH management where strong acids are present.
Concentrated water-based formats for melasma, sun spots and PIH. Pairs with Sodium Hyaluronate for hydration alongside tone correction.
Leave-on emulsions for maintaining even tone and preventing new pigmentation, formulated at pH 5.5–7.0 for daily use on sensitive skin.
Targets PIH and procedure-induced redness through upstream plasmin inhibition. The anti-inflammatory component supports barrier-recovery formats.
Combines with peptides, niacinamide and Natural Antioxidants for pigmentation, texture and oxidative stress in one system.
3% TXA matches 4% hydroquinone on mMASI at 8 weeks, with fewer irritation complaints and no ochronosis risk.
98% HPLC with ≤0.5% single impurity is sufficient for cosmetic actives; 99% pharma grade adds cost, not epidermal performance.
Water-soluble, stable across pH 3–8, compatible with common brightening partners. No solubiliser step required.
COA with HPLC chromatogram, impurity profile, heavy metals and microbiological data, plus MSDS and TDS.
MOQ 25 kg, 1 kg to 25 kg packaging. T/T payment; FOB, CIF, DDU, DDP and express delivery from Beijing, Shanghai or Guangzhou.
Full documents on request. Same quality system across our Natural Antioxidants and Sodium Hyaluronate lines.
Starting materials verified against purity specifications, followed by controlled synthesis, multi-stage crystallisation and washing to ≥98% HPLC with single impurity ≤0.5%. Each batch is tested by HPLC (C18, 220 nm), IR identity, pH, loss on drying, sulphated ash, heavy metals and related substances, then packed with moisture-proof lining and retention samples. Shelf life: 3 years sealed at 15–25°C, protected from light. Custom requests evaluated within 48 hours with a pre-shipment sample.
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Main Product:
Food Additives,
Cosmetic Raw Materials,
Vitamins and Minerals ,
Plant Extract,
Sodium Hyaluronate,
Phytic Acid
