Berberine Hydrochloride (Berberine HCL) - Premium Weight Loss Extract
CNCSBIO’s Berberine Hydrochloride is a high-quality natural extract designed for weight management applications. Derived from premium plant sources, this yellow crystalline powder offers scientifically backed benefits for supporting metabolic health and fat reduction, making it an ideal ingredient for dietary supplements, functional foods, and wellness products.
Basic Information
Berberine HCL is a yellow crystalline powder with no odor and a bitter taste. It is naturally extracted from select medicinal plants including Coptis chinensis, Phellodendri cortex, and other high-purity botanical sources. Our product adheres to strict quality standards to ensure consistency and efficacy for commercial applications.
Core Benefits & Applications
1. Intestinal Flora Regulation: Berberine HCL modulates gut microbiota composition by promoting the proliferation of beneficial probiotics such as Bifidobacterium and Lactobacillus. These friendly bacteria enhance digestion, synthesize essential nutrients (e.g., vitamins, short-chain fatty acids), and inhibit the growth of pathogenic gut bacteria—effectively maintaining intestinal microecological balance, a key factor in weight management.
2. Metabolic Health Enhancement: A balanced gut flora improves intestinal function, boosts nutrient absorption efficiency, and strengthens immunity—while reducing abnormal fat accumulation. Research shows distinct differences in gut microbiota between obese and normal-weight individuals; Berberine HCL alleviates metabolic imbalances in obese populations through targeted flora regulation.
3. Insulin Sensitivity & Fat Metabolism Support: By activating the AMPK (adenylate-activated protein kinase) signaling pathway, Berberine HCL improves insulin sensitivity and reduces insulin resistance. It facilitates glucose transport and fatty acid oxidation, minimizing fat deposition in the liver and muscles. This dual action reduces fat synthesis/storage and promotes fat breakdown, supporting healthy weight loss outcomes.

Frequently Asked Questions (FAQs)
Q1: What is the purity specification of your Berberine HCL?
A: Our standard product offers ≥98% purity, with customizable high-purity grades (up to 99.5%) available to meet specific application requirements. A complete Certificate of Analysis (COA) is provided with each order.
Q2: Are the plant sources of your Berberine HCL sustainably sourced?
A: Yes, we source raw materials from certified organic and sustainable farms, ensuring compliance with international environmental and quality standards. All plant sources undergo rigorous identity and purity testing before extraction.
Q3: What product formulations is Berberine HCL suitable for?
A: It is highly versatile for B2B applications, including dietary supplement capsules/tablets, functional beverages, weight management powders, and natural health products. Its stable crystalline form ensures compatibility with most manufacturing processes.
Q4: Is Berberine HCL safe for commercial use?
A: Our product meets global safety standards (FDA, EU Food Supplements Directive) with low toxicity and no known severe side effects when used as directed. We provide comprehensive safety data sheets (SDS) for regulatory compliance.
Q5: What is the minimum order quantity (MOQ)?
A: Standard MOQ is 1kg, with flexible bulk pricing available for large-scale orders (50kg+). Custom packaging and labeling options are offered for bulk purchases.
Q6: How should Berberine HCL be stored?
A: Store in a cool, dry place (15-25℃) away from direct sunlight and moisture. Sealed properly, it maintains stability for 24 months from the production date.
Q7: Do you provide custom specification development?
A: Yes, we offer OEM/ODM services to tailor purity, particle size, and formulation to your specific product needs. Our R&D team supports technical collaboration for specialized applications.
Q8: Is third-party testing available?
A: We accept third-party testing by accredited laboratories (e.g., SGS, Intertek) at the buyer’s request. All products undergo in-house testing for purity, heavy metals, and microbial contamination before shipment.
CNCSBIO is committed to delivering high-quality Berberine Hydrochloride for global weight management product manufacturers. With strict quality control, reliable supply chains, and professional technical support, we are your trusted partner for natural extract solutions.