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A Pharmaceutical Reactor is more than a stainless steel vessel.
For pharmaceutical and fine chemical production, reactor performance depends on accurate control of temperature, pressure, agitation, material compatibility, heat transfer and product cleanliness.
Our pharmaceutical reactors are engineered for processes including synthesis, crystallization, dissolution, reaction, concentration and formulation.
Each reactor can be customized according to the customer's process conditions, batch size and GMP requirements.
| Parameter | Typical Configuration |
|---|---|
| Reactor Type | Pharmaceutical Process Reactor |
| Working Volume | Customized |
| Total Volume | Customized |
| Design Pressure | Vacuum / Positive Pressure |
| Design Temperature | Customized |
| Operating Temperature | Customized |
| Material | SS316L / Hastelloy / Titanium |
| Surface Finish | Customized |
| Agitator | Anchor / Paddle / Propeller / Customized |
| Heating / Cooling | Jacket / Half Pipe Coil |
| Heating Medium | Steam / Thermal Oil / Hot Water |
| Cooling Medium | Chilled Water / Cooling Water |
| Control | PLC / DCS |
| Cleaning | CIP / SIP Optional |
A pharmaceutical reaction can be highly sensitive to operating conditions.
The reactor can be designed around:
Reaction Temperature
Reaction Pressure
Heating Rate
Cooling Rate
Agitation Speed
Feed Addition Rate
Residence Time
Vacuum Level
Product Viscosity
These parameters are considered when selecting the vessel geometry, agitator and heat-transfer system.
For pharmaceutical applications, the internal surface can be designed to minimize:
Possible features include:
Surface requirements can be specified according to the customer's GMP and validation documentation.
Different products require different mixing strategies.
Suitable for viscous products and wall-scraping applications.
Useful for moderate-viscosity mixing duties.
Suitable for lower-viscosity liquids and improved circulation.
For difficult mixing applications, agitator diameter, speed, shaft length and motor power can be engineered according to the actual viscosity and mixing objective.
When the reaction medium is highly corrosive, conventional stainless steel may not be sufficient.
For high-temperature and aggressive applications, Titanium High Temperature Agitator vessels can be considered where titanium compatibility is required.
For chloride-containing media, Hastelloy Chloride Resistant Agitator vessels can provide an alternative material solution.
For pressurized corrosive mixing applications, Anti-corrosion Mixing Pressure Tanks can also be evaluated.
Material selection should always be based on actual chemical composition, concentration, temperature and pressure.
Reaction temperature control may use:
Jacket
Half-Pipe Coil
Internal Coil
External Heat Exchanger
The heat-transfer system can be designed for:
Typical applications include:
To evaluate a reactor, provide:
Working Volume: ___ L
Batch Volume: ___ L
Product: ___
Viscosity: ___ cP
Density: ___ kg/m³
Reaction Temperature: ___ °C
Operating Pressure: ___ bar
Design Pressure: ___ bar
Agitation Speed: ___ rpm
Heating Medium: ___
Cooling Medium: ___
Material: ___
Surface Finish: ___ Ra
Send your process conditions and batch requirements.
Our engineering team can evaluate the reactor volume, agitator configuration, heat-transfer area, material selection and mechanical design for your application.
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